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There have been reports that the function of BCL-2 and Bax genes leads to defects in spermatogenesis and infertility in mice [68,69]

However, the labelling (M + 4) in metabolites produced after direct metabolism of [U- 13 C] glutamate such as fumarate, malate and aspartate was significantly decreased in FTD3 neurons compared to isogenic controls (with the exception of fumarate and -kg M + 4 in H150, Fig 3 c 25 ), in contrast to the first turn TCA cycle in which metabolites were unmodified in FTD3 neurons compared with isogenic controls

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4 BahureksaL.NajafiB.SalehA.SabbaghM.CoonD.MohlerM.et al (2017)

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