oral melanotic macule pathology a at the wet–dry line of the lower lip. b Melanotic Lingual melanotic macule – the
Description
Images were acquired on a Leica Thunder Live Cell Imager equipped with a HC PL APO 63x/1.20 W CORR objective, LED8, Quad LED filter sets, and a K8 camera

Oncogene 16: 1939-1944.

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Accordingly, RNAi targeting autophagy genes abolishes the lifespan extension induced by the eat-2 mutation or TOR signaling inhibition

L4 gonads, which produce low-fat sperm, had very low levels of fat, as expected (Fig 1C)

We conclude that the mutation-induced defect in PGL-1 NtDD dimerization has a dominant-negative effect that reduces assembly of both PGL-1 and PGL-3 into granules, and that this likely explains the severe fertility defects of PGL-1 dimerization mutants
