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In addition, extracellular lactate stabilizes HIF-2, and HIF-2 then transactivates MYC, increasing the levels of glutamine transporters and GLS1, in turn resulting in increased glutamine catabolism 72

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Toxicol Appl Pharmacol 153(1):109118 Alkreathy HM, Esmat A (2022) lycorine ameliorates thioacetamide-induced hepatic fibrosis in rats: emphasis on antioxidant, anti-inflammatory, and STAT3 inhibition effects

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