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Oxidized forms notably include disulfides, either with another glutathione cysteine residue to produce glutathione disulfide (GSSG) or with a different thiol to form mixed disulfides, as well as more oxidized forms in which the thiol group is converted to sulfenic, sulfinic or sulfonic acids (Foyer and Noctor, 2005)

For instance, in prokaryotes, GSR is found in the periplasm [13,14], while in eukaryotes, it is found in the mitochondria, cytosol, endoplasmic reticulum and nucleus [1517]

It is found in every cell of the body, where it works intracellularly as an antioxidant to protect cells from damage

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