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Szyk A, Deaconescu AM, Piszczek G, Roll-Mecak A

9Rodriguez-Castro KI

Pharmacological inhibitors (e.g., erastin, RSL3) targeting this axis induce ferroptosis (Kim et al., 2020).Parallel ferroptosis-suppressing pathways include:1)FSP1-CoQH 2 axis: FSP1(ferroptosis suppressor protein 1)regenerates reduced coenzyme Q10 (CoQH 2 ), mitigating lipid radical accumulation

The consequences of post-traumatic DC activity in the CNS are controversially discussed and may range from direct beneficial effects in the acute restoration of tissue homeostasis after injury to the initiation of long-term autoreactive T cell and autoantibody responses, which again have the capacity to generate positive or detrimental outcomes 102,103

Annual review of medicine