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Klicek, R., Sever, M., Radic, B., Drmic, D., Kocman, I., Zoricic, I., Vuksic, T., Ivica, M., Barisic, I., Ilic, S., Berkopic, L., Vrcic, H., Brcic, L., Blagaic, A

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All three kratom alkaloids tested inhibited select cytochrome P450 enzymes, suggesting a potential risk for adverse interactions when kratom is co-consumed with drugs metabolized by these enzymes

Roche (5 March 2026)

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NA treatment decreases the serum low-density lipoprotein and triglyceride content and elevates the high-density lipoprotein levels