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We identified Y211 as another residue of interest as it forms part of the carnitine binding site and is one residue downstream Na + -coordinating N210 on TM4

While, down-regulation of the transporter directly confers resistance against the drug, via decreasing the intracellular platinum concentration ( General Features of ATB 0,+ (SLC6A14) ATB 0,+ is a plasma membrane transporter belonging to the SLC6 family that includes amino acid transporters, neurotransmitter transporters, and osmolyte transporters (Pramod et al., 2013)

The homogenate was centrifuged (12,000 g ) at 4C for 10 min to get liquid phase for assays

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Weeks 36 : Noticeable improvements in fat burning and muscle definition, particularly if paired with regular cardio and resistance training