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GSH Insufficiency and Diabetes: Impact on Pancreatic -Cell Function and Insulin Resistance Type 2 diabetes mellitus (T2DM) is characterized by elevated oxidative stress and reduced GSH levels, which detrimentally affect pancreatic -cell function and insulin sensitivity
doi: 10.3390/nu13082861

The appropriate immunogenicity of OMVs enables the recruitment of macrophages to the TME, which might synergize with DOX in vivo
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The oxidized form of GSH is GSH disulfide (GSSG), which can be recycled to GSH by GR using reduced nicotinamide adenine dinucleotide phosphate (NADPH) as the electron donor