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The second is pH-dependent solubility which refers to the solvation equilibrium being affected by the pH of the solution

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Vande Woude, K

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In contrast, CTLs mainly induce cell death through apoptosis in cancer cells, positioning them as crucial elements in the defense against tumors [87]

Initial treatment for patients with neurological involvement follows British National Formulary (BNF) guidance: Hydroxocobalamin 1 mg intramuscularly on alternate days for approximately 2-3 weeks (or until no further improvement) Maintenance therapy then consists of hydroxocobalamin 1 mg intramuscularly every two months Hydroxocobalamin is preferred over cyanocobalamin in the UK due to superior retention and fewer injections required