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In these (known) cases, the HOCl-induced repurposing of proteins is triggered by oxidation of their thiol residues or N-halogenation of their basic amino acids

10.1016/j.juro.2015.02.1786 122

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Plantinga and team found that the ATG16L1 polymorphism in humans is linked to elevated IL-1 and IL-6 production, potentially influencing the inflammatory process in CD