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doi: 10.1093/annonc/mdg301

10.1155/2014/658589 43 MaR.WangX.PengP.XiongJ.DongH.WangL.et al

For instance, analyzing the most recent TCGA multidimensional omics data revealed that multiple iron-related genes ( e.g., scavenger receptor class A member 5 (SCARA5), erythroferrone (ERFE), lipocalin 2, transferrin receptor 2 (TFR2), solute carrier family 11 member 1 (SLC11A1), and cytochrome B reductase 1 (CYBRD1)) were dysregulated in different cancers, and this outcomes may be associated with aberrant DNA methylation[112]

[DOI] [PubMed] [Google Scholar] 286.Schepici G., Bramanti P., Mazzon E

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Therefore, we hypothesize that LA can reactivate Nrf2 by dissociating it from Keap1 and phosphorylating Nrf2 itself, although the mechanisms need further investigation