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treat it with the care it craves

To test the literature-based model, we systematically adjusted the various reaction rates by numerical optimization of the likelihood function to minimize the discrepancy between the time-course of the observed concentrations in the fluorescent reporter cell lines and the corresponding model predictions

[DOI] [Google Scholar] 201.Liu Y., Li C.-L., Xu Q.-Q., Cheng D., Liu K.-D., Sun Z.-Q

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Snchez CA, Li H, Phelps KL, Zambrana-Torrelio C, Wang LF, Zhou P, et al