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VIP affects Th1/Th2 generation indirectly by inhibiting IL-12 production in activated APCs, and directly by blocking IL-12 signaling through the inhibition of JAK2/STAT4 phosphorylation and by inducing c-Maf and JunB (Voice et al

Discussion 1) At the end of the trial it was recorded that 100-102 participants received an active dose of cagrilintide, 99 participants were administered a 3.0 mg dose of liraglutide and 101 participants were given volume-matched placebo

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Funding The authors did not receive any funding for this work

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